Ponazuril Paste For Dogs

Developmental toxicity studies for ponazuril have been done in rats and rabbits 5 rats administered ponazuril orally during gestation were found to ex perience maternal and developmental toxicity at 300 mg kg.
Ponazuril paste for dogs. Ponazuril has broad spectrum activity against coccidia and protozoa. Infection parasitic coccidiosis toxoplasmosis and intestinal amebiasis if you have any questions concerning these medications please consult with your doctor. Veterinarian grade anti diarrhea dogs solution fast relief for dog diarrhea upset stomach cramping discomfort dog gas kaolin pectin 8 oz. In gestat ing rabbits 3 different doses 10 mg kg 30.
Ponazuril is an active metabolite of toltrazuril. Ponazuril should be used cautiously in pregnant or lactating pets and dogs with susceptible to dry eye keratoconjunctivitis sicca kcs. Daugschies a mundt hc letkova v. Listler al nichols j hall k camp j mohamed as.
These articles from petmd may be of interest to you. Ponazuril is given by mouth and is used on and off label to treat protozoal parasites in a variety of animal species. Manufactured by bayer animal health this medication is indicated for use in horses and other large ruminants but it may be used in dogs when compounded or diluted. Schering intervet d panacur dewormer horse paste 10 100mg.
Furr and kennedy 8 evaluated the pharmacokinetics of ponazuril in serum and csf in normal horses treated daily at 5 mg kg for 28 days. Decoquinate is an easy way to prevent coccidia simply add it to your puppy s food. Unlike sulfa based antibiotics ponazuril actively kills the coccidia microorganisms. Side effects are uncommon but may include soft stools.
The alternate chemical name for ponazuril is toltrazuril sulfone. Feed the last two weeks of pregnancy. Decoquinate works by preventing coccidia from reproducing so they die of attrition old age. Ponazuril is an oral paste solution sold under the brand name marquis.
At the 2014 maddie s shelter medicine conference at the university of florida maddie s shelter medicine resident staci cannon dvm presented the results of a study that looked at three different dosages of ponazuril paste in cats and dogs that had confirmed coccidiosis. Prevention of coccidia in dogs. A single dose of 50mg kg. In 2011 the european committee for medicinal products for veterinary use approved a combination product of toltrazuril and emodepside for use in the dog to.
At 90 mg kg a noel was found. Safeguard horse dewormer 25 gm. Ponazuril oral paste prescribed for. Toltrazuril treatment of cystoisosporosis in dogs under experimental and field conditions.
The noel for dogs was 200 ppm. Use of ponazuril paste to treat coccidiosis in shelter housed cats and dogs. Do not use in pets that are allergic to it. Clinical pharmacology the activity of ponazuril has been demonstrated in several apicomplexans 1 6 lindsay dubey and kennedy 7 showed that the concentration of ponazuril necessary to kill sarcocystis neurona in vitro was 0 1 to 1 0 µg ml.
The mother should also be fed puppy food with decoquinate. 50 mg kg every 24 hours for 3 days.