Reed Sternberg Cell Adalah

In the vast majority of cases the immunoglobulin genes of reed sternberg cells have undergone both vj recombination and somatic hypermutation establishing an origin from a germinal center or postgerminal center b cell. The reed sternberg cells are identified as large often bi nucleated cells with prominent nucleoli and an unusual cd45 cd30 cd15 immunophenotype. Reed 1874 1964 american pathologist.

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